General Chat

Top tip - using the Genes Reunited community

Welcome to the Genes Reunited community boards!

  • The Genes Reunited community is made up of millions of people with similar interests. Discover your family history and make life long friends along the way.
  • You will find a close knit but welcoming group of keen genealogists all prepared to offer advice and help to new members.
  • And it's not all serious business. The boards are often a place to relax and be entertained by all kinds of subjects.
  • The Genes community will go out of their way to help you, so don’t be shy about asking for help.

Quick Search

Single word search

Icons

  • New posts
  • No new posts
  • Thread closed
  • Stickied, new posts
  • Stickied, no new posts

Blood Groupings

Page 0 + 1 of 3

  1. 1
  2. 2
  3. 3
  4. »
ProfilePosted byOptionsPost Date

~Summer Scribe~

~Summer Scribe~ Report 31 Oct 2008 20:24

Rose, you would think so, wouldn't you? As there's more and more mixing. I have to admit that I was surprised it was so high. I thought it would be rarer. And maybe that example you gave explains why B is rarer than A and O. It's all very interesting.

Click ADD REPLY button - not this link!

Click ADD REPLY button - not this link! Report 31 Oct 2008 19:58

With O being recessive and A and B being dominant I assume this means there will be less type O people as the years go on?

I know different blood types are better at fighting off diseases. B types, for instance, weren't good at fighting off the plague.

Rose

Sue in Somerset

Sue in Somerset Report 31 Oct 2008 19:31

No she hasn't any kids but I'll bear that in mind to tell her about it.

Sue
x

~Summer Scribe~

~Summer Scribe~ Report 31 Oct 2008 19:02

Sue, I think it's possible that what they're really getting is a weak positive, by the sound of it. Although from what I've read it said they tend not to use that term much anymore, perhaps they replaced it with borderline (the do seem to like it eg borderline diabetic). Does she have children? I would think it's an issue that would need clearing up for her when she's having kids. From what I understand, people with RhD neg are ok on the first exposure, it's the second exposure that causes the problem because antibodies have been generated to it (hence why they give the Anti-D jab after the first baby).

To be sure, BC, less so in Ireland though. LOL ;-))

haven't seen her, maybe she fainted at the mention of all this blood?

Charlie chuckles

Charlie chuckles Report 31 Oct 2008 18:53

Proper common me--O+

ButtercupFields

ButtercupFields Report 31 Oct 2008 18:19

I am A Pos...am I common as muck then, Liz? lol BC XX

ps....am looking for Hayley, anyone seen her???

Sue in Somerset

Sue in Somerset Report 31 Oct 2008 18:14

Now here is something to puzzle over Summer.

My daughters are both blood donors. My younger one has been sometimes told she is B+ and sometimes B-

She was a bit worried about this in case she ever needed blood and was given the wrong sort but has been told that she is a borderline positive/negative.

I'd never heard of that before so it's a bit weird.

Sue

Claddagh

Claddagh Report 31 Oct 2008 17:14

Thanks for your very succinct explanation SS.I have read and reread your post, but my eyes are rolling around like Cathrine wheels.It's not you but ME.All I know is that when my eldest child was born(at home), the gp said something about the Rhesus factor, my daugher was a bit yellow, but he didn't send her to hospital.Didn't explain anything either.Mind you, he was not such a great gp.Lucky I didn't know how dangerous it could be back then.

~Summer Scribe~

~Summer Scribe~ Report 31 Oct 2008 17:06

No worries Joan, that's some of the simpler genetics I had to learn, no wonder I did a physiology degree LOL.

I must correct myself though about the Rhesus D. Apparently two positive parents can have a negative child. I won't bore you with the genetics of that. But two negative parents can't have a positive child.

MaggyfromWestYorkshire

MaggyfromWestYorkshire Report 31 Oct 2008 17:00

I'm common as muck me, O+, but that also means that more people need my blood!!

blackrose

blackrose Report 31 Oct 2008 16:58

I have a card which ive carried since pregnant with my first child in 1981 when it was discovered I had a very rare Rh-. There isnt an initial AB or O just Rh- dd. I havent a clue what this means - help am I an alien. Just got told that only 2% have this group. Whenever Ive had a baby or an op blood has been taken from me beforehand incase I need it. My husband is Rh-which helped when I was pregnant.

~Summer Scribe~

~Summer Scribe~ Report 31 Oct 2008 16:50

Claddagh, I was no good at it at school, only as an adult did I get into science geekery. I find it difficult to explain. I'll give it a go at making it more user friendly LOL.

As you know there are 4 blood groups A, B, AB and O. However there are two sets of genes that determine the blood group (one from each parent).

So, this means you have two copies of the blood group gene. And they can come in six different combinations depending on what you get from your parents: AA AO OO BB BO AB

As O is a recessive gene, the only time you'll see it as the blood group is when the two parents both pass an O pass on to their child. That means a person with an O blood group always has the genes OO (one from each parent).

The recessive O means that if one parent gives an O and the other parent gives A or B, they will have a blood group of A or B.

A person who is A can either have two A's (AA) or an A and an O (AO).

A person who is B can either have two B's (BB) or a B and an O (BO).

A person who has an AB blood group must have both an A and a B as they are what is called co-dominant (one can't exert dominance over the other - they won't give way LOL).

When you have your children, you only give one copy of the genes to your child, the other comes from your partner. So, if you are O then you can only give an O, if you are AB you could give either A or B, but with a blood group of A or B it's harder to predict because you don't know what the two genes are (they could be AA or AO, BB or BO)

So with that in mind if for example you're AA you could give only A.

But if you are AO you could give either A or O. If your partner is the same (AO), then then you could have a child that is AA or AO or OA or OO, Leaving a 1 in 4 (or 25%) chance of have an O blood grouped child and 3 in 4 (75%) chance of an A.

But, if you're A and your partner is B... and the genes are both AA and BB then you will have only AB children.

If one has an O gene (AO & BB) then you could have AB or BO so either a AB blood group or a B. (You can reverse that for AA and BO).

If you are both have an O gene and either an A or B (ie AO and AO, BO and BO, AO and BO) then you could give either an O or the dominant gene. The result is your child could be A, B, AB or O there is a 25% chance for each.

Parents
blood.........parents
group........genes:...........children's blood group
O & O......OO and OO =....O
O & A......OO and AO =.....A
O & A......OO and AA = ....A
O & B......OO and BO =....B
O & B......OO and BB = ....B
A & A......AA and AA = .....A
A & A......AO and AA = ....A
A & A......AO and AO = .....A or O
B & B......BB and BB = .....B
B & B......BO and BB = .... B
B & B......BO and BO = .....B or O
AB&AB...AB and AB = .....AB
AB&A.....AB and AA = .....A or AB
AB &A....AB and AO = ......A, B or AB
AB&B.....AB and BB = .....B or AB
AB&B.....AB and BO =.......A, B or AB
A & B......AA and BB =.....AB
A & B.....AO and BO =.......A, B, AB or O


(think that's them all LOL) Does that help any?

On top of that you can either be Rhesus D (Rh D) positive or negative and that's what the pos or neg stands for when you give your blood group.

AnninGlos

AnninGlos Report 31 Oct 2008 16:23

Eileen, you are not alone. I am just glad to know I have some (blood I mean!)

~Summer Scribe~

~Summer Scribe~ Report 31 Oct 2008 16:05

LOL Cazzles, you'll have to go to Turkey where you'll be less common PMSL

Interestingly, was just looking at a Rhesus fact sheet thing and it seems RH neg is more prevelant in Europe and western countries. Very rare in Asia. But then that's statistics and we all know how reliable they can be.

Cumbrian Caz~**~

Cumbrian Caz~**~ Report 31 Oct 2008 15:56

Im common Liz, o positive!

Caz xx

AnninGlos

AnninGlos Report 31 Oct 2008 15:49

I am A Rh neg. Don't know what my parents were and don't know what my children are either, I didn't have any problems when either of them were born

Ann
Glos

~Summer Scribe~

~Summer Scribe~ Report 31 Oct 2008 15:34

It depends Joan.

B refers to the phenotype (ie what is seen) where as the genotype (at the genetic level) could be BB or BO. Therefore if both you and your hubby were BO you could have either a B+ or O+ child although I think it would statistically be in favour of B+ (75% chance), this is because the O allele is recessive and B is dominant. AB occurs because both A & B are what are called co-dominant.

With my mum and dad, one is A the other is B. They could have any combination A, B, AB or O depending on what their base genotype are (ie if they were AO or AA, BO or BB). If they were AA and BB I think that they could have only AB children. As I recall two Rh+ parents can have only Rh+ children (but I know less about the Rhesus factor).

Thanks for the revision session, I did all this at uni in my second year...thought I'd forgotten most of it. Hope it makes sense.

Merlin

Merlin Report 31 Oct 2008 15:28

You still have Blood???.Don,t let Gordon Brown Know or he,ll be after it,not a lot of people have any left now,He,s took the lot.**M**.:o)))>.

~Summer Scribe~

~Summer Scribe~ Report 31 Oct 2008 15:24

I am still so surprised at the number of O negs on here.

~Summer Scribe~

~Summer Scribe~ Report 31 Oct 2008 14:39

Very true Elizabeth, sad how many children must have been lost before.